Enterovirus by Nucleic Acid Amplification
Meningitis, Viral, Virus, URI, Upper Respiratory Infection, PCR, Real-Time PCR , WARDE: EVPCR, EPIC: LAB6860, SOFT: IEVNA
Specimen Collection Criteria
Collect: One of the following specimen types:
- Cerebrospinal Fluid (CSF) in a sterile collection container. (Min: 0.5 mL)
- Specimen must be refrigerated within one hour or collection.
- Nasopharyngeal (NP) Swab in viral transport media (UVT, UTM).
- Bronchoalveolar lavage/wash in sterile screw-capped plastic container 1.0 mL (Min: 0.5 mL).
- Stool in sterile screw-capped plastic container 2.0 mL (Min: 1.0 mL) for liquid stool or marble-size solid stool.
- Urine in a sterile screw cap container (Min: 1.0 mL)
- Bone Marrow in EDTA, 1.0 mL (Min: 0.5 mL).
- Whole blood in EDTA, 2.0 mL (Min: 1.0 mL).
- Swab specimens (throat, oral, dermal, ocular, esophagus) in viral transport medium (UVT, UTM).
- Biopsy/tissue specimens in saline or viral transport medium (Snap frozen -20°C).
Physician Office/Drawsite Specimen Preparation
- CSF: Maintain specimen refrigerated (2-8°C or 36-46°F). Specimens not received in the Laboratory within 24 hours of collection must be frozen (-20°C/-4°F or below).
- NP Swabs: Maintain specimen in viral transport medium (UVT, UTM), refrigerated (2-8°C or 36-46°F) or frozen (-20°C/-4°F or below).
- Biopsy/tissue specimens: Maintain specimen frozen (-20°C/-4°F or below)
For all other specimen types: Maintain specimen refrigerated (2-8°C or 36-46°F).
Preparation for Courier Transport
Transport: CSF in a sterile collection container (Min: 0.5 mL), NP swab in viral transport medium, throat, oral, dermal, ocular, or esophagus swabs in viral transport medium, bone marrow in EDTA (Min: 0.5 mL), whole blood in EDTA (Min: 1.0 mL), biopsy/tissue specimens in saline or viral transport medium: refrigerated (2-8°C or 36-46°F) or frozen (-20°C/-4°F or below).
- Specimens submitted on dry swabs.
- Specimens submitted in bacterial transport systems.
- Specimens submitted on cotton or calcium alginate swabs, or on wooden shaft swabs.
CSF and NP Swabs: Sunday - Saturday.
Results available within 24-48 hours.
All other sample types: Monday – Saturday
Results available 2-4 days.
Nucleic Acid Amplification (FDA Approved).
A negative result does not rule out Enterovirus infection.
This assay provides a highly sensitive and specific test for the diagnosis of enteroviral infection.
The Enteroviruses consist of a group of small RNA viruses within the family Picornaviridae and include the poliovirus and the non-polioviruses: coxsackieviruses group A and B, echoviruses and the numbered enteroviruses. Enterovirus infections include aseptic meningitis, encephalitis, and upper respiratory tract infections.
WARDE: EVPCR, EPIC: LAB6860, SOFT: IEVNA
Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.
This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.