Lab Test

Anti Striated Muscle Antibody

Anti-Striated Muscle Antibody, ASTM, ARUP #50746, EPIC: LAB6812, SOFT: XASTM

Test Codes

ARUP #50746, EPIC: LAB6812, SOFT: XASTM

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.15 mL)

Rejection Criteria

  • Hemolyzed specimens.
  • Severely lipemic specimens.
  • Specimens not collected and processed as indicated.

In-Lab Processing

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Minimum: 0.15 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday – Saturday.
Results available in 2-6 days.

Reference Range

Less than 1:40.

Test Methodology

Semi-Quantitative Indirect Fluorescent Assay.

Interpretation

Titers greater than or equal to 1:80 are suggestive of myasthenia; however, striated muscle antibody can be found in rheumatic fever, myocardial infarction, and a variety of post-cardiotomy states.  All positives will be titered to endpoint. If Striated Muscle Antibody is greater than 1:40, then a titer will be added.

Clinical Utility

Anti-striated muscle antibody assay is used as an aid in the diagnosis of thymoma-associated myasthenia gravis.

CPT Codes

86255, 86256 (if reflexed).

Contacts

Last Updated

10/23/2019

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This directory currently reflects information only for specimens collected and/or processed at the
Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.