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Beaumont Laboratory

Schistosoma Antibody, IgG

ARUP #99411, EPIC: LAB6332, SOFT: XSHIS

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells within two hours of collection. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.1 mL)

Rejection Criteria

  • Hemolyzed specimens.
  • Icteric specimens.
  • Lipemic specimens.
  • Turbid specimens.
  • Specimens not collected and processed as indicated.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Thursday.
Results available in 2-9 days.

Reference Range

Negative: Less than 0.20 OD - No significant level of IgG antibody to Schistosoma detected.
Positive: Greater than or equal to 0.20 OD - Presumptive evidence of a current or past infection with Schistosoma.

Test Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay.

Interpretation

This assay is highly specific (99%) and sensitive (96%) for detection of infection caused by S. mansoni. Although the assay is also highly specific for infections caused by other Schistosoma species (S. japonicum, S. haematobium, S. mekongi), its sensitivity for these infections is lower (55%). Antibody levels do not correlate with the intensity of infection.

Clinical Utility

This assay aids in the diagnosis of schistosomiasis.

CPT Code

86682.

Test Codes

ARUP #99411, EPIC: LAB6332, SOFT: XSHIS

Last Updated

12/12/2016

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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.