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Beaumont Laboratory

Selenium

ARUP #25023, EPIC: LAB6149, SOFT: XSE

Instructions

Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).

Specimen Collection Criteria

Collect (preferred specimen): One plain Royal Blue-top tube with no additive.
Also acceptable: One Royal Blue-top EDTA tube.

Physician Office/Drawsite Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a metal free transport tube within six hours of collection. Maintain at room temperature (20-26°C or 68-78.8°F) prior to transport.

Preparation for Courier Transport

Transport: 2.0 mL serum or plasma, at room temperature (20-25°C or 68-77°F). (Min: 0.5 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated. 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Indefinite
Refrigerated (2-8°C or 36-46°F): Indefinite
Frozen (-20°C/-4°F or below): Indefinite

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Sunday - Saturday.
Results available in 2-4 days.

Reference Range

23-190 mcg/L.

Test Methodology

Quantitative Inductively Coupled Plasma/Mass Spectrometry.

Interpretation

Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentratons of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).

Clinical Utility

Selenium is an essential constituent of glutathione peroxidase and deficiencies have been linked to increased risk of cancer. There is also evidence that selenium is essential for normal thyroid metabolism. A recent report claims a link between selenium and HIV, wherein selenium depletion increases the rate of virus replication and speeds the development of full-blown AIDS in infected individuals. Acute selenium overdose is associated with hair and nail loss, dermatitis, tooth decay, and neurological symptoms. The selenium assay is used for the therapeutic monitoring of selenium replacement therapy and toxicity assessment of selenium.

CPT Code

84255.

Test Codes

ARUP #25023, EPIC: LAB6149, SOFT: XSE

Last Updated

12/12/2016

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.