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Beaumont Laboratory

Testosterone, Total, Adult Male

Total Testosterone - Testing for Adult Males, Testosterone, Adult Male, Antrim # 19638, EPIC: LAB7029, SOFT: TESTG

Instructions

This test measures total testosterone by chemiluminescent immunoassay and is not appropriate for females or children. Please refer to Testosterone, Total, Females or Children.

Specimen Collection Criteria

Collect: One Gold-top SST tube. (Minimum Whole Blood: 4.0 mL)

  • Contact the Laboratory for acceptability of other tube types.
  • It is recommended that the specimen be collected between 6:00 -10:00 a.m., however, it is not required and specimens collected at other times will not be rejected. 

Physician Office/Drawsite Specimen Preparation

Let SST specimens clot 30-60 minutes then immediately centrifuge to separate serum from cells. Refrigerate (2-8°C or 36-46°F) the centrifuged SST tube within two hours of collection.

Preparation for Courier Transport

Transport: Centrifuged SST tube, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)

Rejection Criteria

  • Grossly hemolyzed specimens.
  • Red-top tubes with serum not separated from cells within two hours of collection.

Storage

Specimen Stability for Testing:

Centrifuged SST Tubes and Microtainers® with Separator Gels
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Red-top Tubes and Microtainers® without Separator Gels
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Unacceptable

Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 2-4 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 7 days

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Farmington Hills Chemistry Laboratory.
Royal Oak Automated Chemistry Laboratory.

Performed

Sunday - Saturday, 24 hours a day.
Results available within 24 hours of receipt in the Laboratory.

Reference Range

Adult Male (18 Years and Older): 240 - 1048 ng/dL.

Test Methodology

Chemiluminescent Immunoassay.

Interpretation

  • Heterophilic antibodies in human serum can react with reagent immunoglobulins, interfering with in vitro immunoassays. Patients routinely exposed to animals or animal serum products can be prone to this interference and anomalous high values can be observed. Additional information may be required for diagnosis.
  • Clinical evaluation of serum testosterone, along with serum luteinizing hormone (LH), assists in evaluation of hypogonadal males.
  • Major causes of lowered testosterone in males include hypogonadotropic hypogonadism, testicular failure, hyperprolactinemia, hypopituitarism, some types of liver and kidney diseases, and critical illness.
  • Testosterone levels are much lower in females compared to males.
  • Increased serum testosterone levels in females may be indicative of polycystic ovary syndrome and adrenal hyperplasia, among other conditions. Clinical manifestations of excess testosterone in females include: infertility, hirsutism, amenorrhea, and obesity.

Clinical Utility

Serum testosterone assays aid in the evaluation of males with erectile dysfunction, gynecomastia, osteoporosis, infertility, delayed or precocious puberty, and for monitoring replacement therapy, evaluation of women with hirsutism, virilization, and oligomenorrhea, and in the evaluation of infants with ambiguous genitalia and/or virilizing syndromes.

CPT Code

84403.

Test Codes

Antrim # 19638, EPIC: LAB7029, SOFT: TESTG

Last Updated

01/14/2017

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.