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Beaumont Laboratory

Creatinine, Urine

Urine Creatinine, 24 Hour Urine: EPIC: LAB5444, SOFT: CRU24, Random Urine: EPIC: LAB5035, SOFT: CREAU

Instructions

Note: 24 hour and random urine specimens MUST be collected separately. See below for collection criteria.

Specimen Collection Criteria

Collect: 24 hour urine or timed urine specimen with a 24 hour urine container with no preservatives.
Also acceptable: Random urine specimen in a screw-capped container (preferred) or another sterile collection cup. Preservatives are not acceptable for random urine specimens. (Minimum: 20 mL)

  • Refer to the table of Urine Preservative Options when multiple tests are requested.
  • Keep 24 hour urine specimen iced or refrigerated during collection.
  • Include start and end dates and times for the collection period on the specimen container.
Urine Preservative Options
No Preservative
6N Hydrochloric Acid
Boric Acid (10g)
Sodium Carbonate
50% Acetic Acid
PREFERRED
Acceptable
Acceptable
Acceptable
Acceptable

Physician Office/Drawsite Specimen Preparation

Maintain specimens refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: Entire 24 hour urine collection, timed urine, or the random urine, refrigerated (2-8°C or 36-46°F).

Rejection Criteria

  • Specimens not collected and processed as indicated.

Storage

Specimen Stability for Testing:

Room temperature (20-26°C or 68-78.8°F): 4 hours
Refrigerated (2-8°C or 36-46°F): 4 days
Frozen (-20°C/-4°F or below): For longer storage.

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days (Royal Oak and Troy store an aliquot for 30 days.)

Laboratory

Farmington Hills Chemistry Laboratory.
Grosse Pointe Chemistry Laboratory.
Royal Oak Automated Chemistry Laboratory.
Troy Chemistry Laboratory.

Performed

Sunday - Saturday.
Routine results available within 24 hours. 

Reference Range

Urine Creatinine: 800 - 2,000 mg/24 hours.
Normal ranges for random urines or for collections other than 24 hours have not been established.

Test Methodology

Spectrophotometry.

Interpretation

  • Urine creatinine may be increased due to exercise, infections, meat meals, diabetes mellitus, hypothyroidism, and acromegaly.
  • It may be decreased in advanced renal disease, diseases with decreased muscle mass, muscular dystrophy, inflammatory or metabolic diseases of muscle, hyperthyroidism, anemia, leukemia, and vegetarian diets. This test is NOT useful in evaluating renal function except as part of a Creatinine Clearance test.

Clinical Utility

This assay aids in the diagnosis and management of renal diseases (when done as part of a Creatinine Clearance test), in monitoring renal dialysis, and as a calculation basis for measuring other urine analytes.

CPT Code

82570.

Test Codes

24 Hour Urine: EPIC: LAB5444, SOFT: CRU24, Random Urine: EPIC: LAB5035, SOFT: CREAU

Last Updated

12/06/2017

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.