Lab results are too important to go anywhere else

Beaumont Laboratory

Methadone Screen, Urine

Urine Methadone Screen, Antrim #17075, EPIC: LAB7013, SOFT: MET9

Specimen Collection Criteria

Collect: 50 mL random urine in a screw-capped container (preferred) or other sterile collection cup. (Min: 30 mL)

  • Refrigerate the specimen immediately after collection.
  • Record the exact time of specimen collection on the container or in the computer system.

Physician Office/Drawsite Specimen Preparation

Maintain specimen refrigerated (2-8°C or 36-46°F) prior to transport.

Preparation for Courier Transport

Transport: 50 mL urine, refrigerated (2-8°C or 36-46°F). (Min: 30 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.
  • Urine Vacutainer® tubes. Urine received in a glass or plastic tube with a rubber stopper may contain insufficient sample volume, preclude confirmatory testing, and give rise to contaminants and artifacts.


Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 24 hours
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Frozen (-20°C/-4°F or below): 2 months


Farmington Hills Chemistry Laboratory.
Grosse Pointe Chemistry Laboratory.
Royal Oak Toxicology Laboratory.
Troy Chemistry Laboratory.

Note: Screens are performed at Farmington Hills, Grosse Pointe, Royal Oak, and Troy. All confirmations are performed at Royal Oak.


Sunday - Saturday, 24 hours a day.
STAT screen results available within 1 hour of receipt in the Laboratory, and confirmation within 12 hours.
Routine results available within 24 hours. 

Reference Range

None Detected (Positive Cutoff: 300 ng/mL).

Test Methodology

Screen: Enzyme Immunoassay.
Confirmation: Gas Liquid Chromatography/Mass Spectrometer (GC/MS).

The confirmation component of this test was developed by Beaumont Health. It has not been cleared or approved by the FDA. The laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.


Concentrations of drugs and/or metabolite(s) detected in urine have not been correlated to drug levels in the bloodstream or with the degree of impairment. The presence of a drug and/or metabolite(s) in urine is only an indication of previous drug exposure.

Clinical Utility

Methadone is a synthetic narcotic analgesic that is similar to morphine. Methadone is commonly prescribed as the drug of choice in the maintenance treatment of heroin addicts. Patients in methadone therapy are routinely screened for methadone as a measure of compliance. This assay is used to aid in the diagnosis and treatment of methadone use or abuse. This assay provides a preliminary analytical result. Positive results are confirmed by chromatographic methods.

CPT Code

80307, 80358 (alternate: G0479, G0480).

Test Codes

Antrim #17075, EPIC: LAB7013, SOFT: MET9

Last Updated


Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.