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Beaumont Laboratory

Lidocaine Level

Xylocaine, Anrim #17245, EPIC: LAB5399, SOFT: LIDOC

Specimen Collection Criteria

Collect: One plain Red-top tube. (Minimum Whole Blood: 2.0 mL)

Do not use Serum Separator Tubes.
Time of Collection:
 Trough, just prior to the next dose.
Record the exact time of specimen collection on the tube or in the computer system.

Physician Office/Drawsite Specimen Preparation

Let specimens clot 30-60 minutes. Refrigerate (2-8°C or 36-46°F) the collection tube within two hours of collection. (Min: 2.0 mL blood)

Preparation for Courier Transport

Transport: Collection tube, refrigerated (2-8°C or 36-46°F). (Min: 2.0 mL blood)

Rejection Criteria

  • Serum Separator (SST) tubes.
  • Severely lipemic or hemolyzed specimens. 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 2 hours
Refrigerated (2-8°C or 36-46°F): 8 hours
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Frozen (-20°C/-4°F or below): 2 months

Laboratory

Royal Oak Toxicology Laboratory.

Performed

Sunday - Saturday, 24 hours a day.
STAT results available within 3 hours of receipt in the Laboratory.
Routine results available within 24 hours.

Reference Range

Therapeutic Range: 2-5 mcg/mL.
Critical Range: Greater than 7 mcg/mL.

Test Methodology

Gas Liquid Chromatography with Nitrogen Phosphorus Detection (GC/NPD).

This test was developed and its performance characteristics determined by Beaumont Health. It has not been cleared or approved by the FDA. The Laboratory is regulated under CLIA as qualified to perform high-complexity testing. This test is used for clinical purposes and should not be regarded as investigational or for research.

Interpretation

Long term Lidocaine infusions exhibit time-dependent decreases in clearance. Serum concentrations may achieve higher levels than predicted.

Clinical Utility

Lidocaine is used as a local anesthetic and to treat ventricular arrhythmias, primarily during heart surgery or after a myocardial infarction. This assay is used to monitor the therapeutic drug level and evaluate the toxicity of lidocaine.

CPT Code

80176.

Test Codes

Anrim #17245, EPIC: LAB5399, SOFT: LIDOC

Last Updated

09/19/2016

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.