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Beaumont Laboratory

Melatonin

ARUP #98816, EPIC: LAB6299, SOFT: XMELA

Specimen Collection Criteria

Collect: Two Lavender-top EDTA tubes
Also acceptable: One plain Red-top tube.

  • Send specimen for processing immediately after collection.

Physician Office/Drawsite Specimen Preparation

Centrifuge to separate plasma or serum from cells within 2 hours of collection. Transfer plasma or serum to a plastic transport tube and freeze (-20°C/-4°F or below).

Preparation for Courier Transport

Transport: 2.0 mL plasma or serum, frozen (-20°C/-4°F or below). (Min 0.5 mL)

Rejection Criteria

  • Hemolyzed specimens.
  • Lipemic specimens.
  • Specimens not collected and processed as indicated.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 48 hours
Frozen (-20°C/-4°F or below): 3 months

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Wednesday.
Results available in 3-11 days.

Reference Range

By report.

Test Methodology

Quantitative Radioimmunoassay (RIA).

Interpretation

Melatonin values vary throughout the day with the peak time of production during the night. Melatonin levels drop dramatically after exposure to bright light.

Melatonin has a stimulatory and suppressive feedback on Gonadotropin release depending on Melatonin level.

Clinical Utility

Patients with cancer frequently have decreased levels of Melatonin as do patients with impaired central nervous system function. Elevated levels can be found in sympathetic orthostatic hypotension.

CPT Code

83519.

Test Codes

ARUP #98816, EPIC: LAB6299, SOFT: XMELA

Last Updated

06/21/2017

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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.