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Beaumont Laboratory

Thyroglobulin by LC-MS/MS

This test is subject to pathology approval prior to sending to the reference laboratory for testing., ARUP #2006550, Order as a Miscellaneous Sendout.


This test is only available to Endocrinologists and Nuclear Medicine Physicians for thyroglobuin antibody positive patients who are being treated or monitored for thyroid cancer.

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One Dark Green-top Lithium or Sodium Heparin tube.

Physician Office/Drawsite Specimen Preparation

Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.5 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Min: 0.7 mL)

Rejection Criteria

  • Specimens not collected and processed as indicated.


Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.


Sent to ARUP Laboratories, Salt Lake City, UT.


Monday, Wednesday, Saturday.
Results available in 2-7 days.

Reference Range

6 - 36 Months: 7.4-48.7 ng/mL.
4 - 7 Years: 4.1-40.5 ng/mL.
8 -17 Years: 0.8-29.4 ng/mL.
18 Years and Older: 1.3-31.8 ng/mL.

Test Methodology

High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS).


The lower limit of detection for Thyroglobulin by LC-MS/MS is 0.5 ng/mL.

Clinical Utility

This test is recommended for quantifying thyroglobulin in thyroglobulin antibody positive patients who are being treated or monitored for thyroid cancer.

CPT Code


Test Codes

ARUP #2006550, Order as a Miscellaneous Sendout.

Last Updated


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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.