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Beaumont Laboratory

Soluble Liver Antigen Antibody, IgG

SLA, ARUP #55235, EPIC: LAB6858, SOFT: XSLAG

Specimen Collection Criteria

Collect (preferred specimen): One Gold-top SST tube.
Also acceptable: One plain Red-top tube.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.3 mL)

Rejection Criteria

  • Hemolyzed specimens.
  • Lipemic specimens.
  • Specimens not collected and processed as indicated. 

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): 48 hours
Refrigerated (2-8°C or 36-46°F): 14 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Sunday, Tuesday, Thursday.
Results available in 2-5 days.

Reference Range

Negative: 0.0-20.0 U.
Equivocal: 20.1-24.9 U.
Positive: Greater than or equal to 25.0 U. 

Test Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay.

Interpretation

The presence of SLA antibodies has almost 100% specificity for autoimmune hepatitis, although only 12-30% have these antibodies. Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.

CPT Code

83516.

Test Codes

ARUP #55235, EPIC: LAB6858, SOFT: XSLAG

Last Updated

03/11/2016

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This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.