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Beaumont Laboratory

Inflammatory Bowel Disease Serology

IBD Panel, MAYO: IBDP, EPIC: LAB6280, SOFT: XIBDS

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also acceptable: One Gold-top SST tube.

Physician Office/Drawsite Specimen Preparation

Let specimen clot 30-60 minutes then centrifuge to separate serum from cells. Transfer serum to plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 0.5 mL serum, refrigerated (2-8°C or 36-46°F). (Min: 0.5 mL)

Rejection Criteria

  • Grossly hemolyzed specimens.
  • Grossly lipemic specimens.
  • Specimens not collected and processed as indicated.

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): 21 days
Frozen (-20°C/-4°F or below): 21 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Sendout Laboratory with any questions.

Laboratory

Sent to Mayo Medical Laboratories, Rochester, MN.

Performed

Varies.
Results available in 2-3 days.

Reference Range

By report.

Test Methodology

Enzyme-Linked Immunosorbent Assay (ELISA)/Indirect Fluorescent Assay (IFA).

Interpretation

The term "inflammatory bowel disease" (IBD) is often used to refer to 2 diseases, ulcerative colitis (UC), and Crohn's disease (CD), that produce inflammation of the large or small intestines.

Patients with IBD have been shown to have antibodies in serum that help to distinguish between UC and CD. Patients with UC often have measurable neutrophil atypical perinuclear anti cystoplasmic antibodies (Atypical P-ANCA), which react with as yet uncharacterized target antigens in human neutrophils; whereas patients with CD often have measurable antibodies, which react with the Saccharomyces cerevisia strain Su 1.

Clinical Utility

As an adjunct in the diagnosis of UC and CD in patients suspected of having IBD.

CPT Code

86671x2, 86255.

Test Codes

MAYO: IBDP, EPIC: LAB6280, SOFT: XIBDS

Last Updated

06/07/2017

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.

This directory currently reflects information only for specimens collected and/or processed at the Farmington Hills, Grosse Pointe, Royal Oak, and Troy campuses.