Digoxin Level, Serum
Lanoxin
Test Codes
EPIC: LAB5038, Beaker: DIG, Antrim: 18285
Department
Chemistry
Specimen Collection Criteria
Collect (preferred specimen): One plain Red-top tube (Minimum Whole Blood: 1.0 mL)
Also acceptable (not preferred): One Gold-top SST tube.
- See Minimum Pediatric Specimen Requirements for Microtainer® collection.
- Draw specimen at least 6 hours following last dose.
- Record the exact time of specimen collection on the tube or in the computer system.
Physician Office/Draw Specimen Preparation
Let specimens clot 30-60 minutes and refrigerate (2-8°C or 36-46°F) within two hours of collection. (Minimum: 1.0 mL blood)
Preparation for Courier Transport
Transport: Collection tube, refrigerated (2-8°C or 36-46°F). (Minimum: 1.0 mL blood)
Rejection Criteria
- Plasma specimens.
- Severely lipemic or hemolyzed specimens.
In-Lab Processing
Let specimens clot 30-60 minutes and centrifuge to separate serum from cells. Deliver an aliqout of serum or the collection tube immediately to the appropriate testing station.
Storage
Specimen Stability for Testing:
Collection Tubes
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable
Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 24 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 3 months
Specimen Storage in Department Prior to Disposal:
Refrigerated (2-8°C or 36-46°F): 7 days
Laboratory
Canton Laboratory
Dearborn Chemistry Laboratory
Farmington Hills Chemistry Laboratory
Grosse Pointe Chemistry Laboratory
Lenox Main Laboratory
Livonia Main Laboratory
Royal Oak STAT Laboratory
Taylor Chemistry Laboratory
Trenton Chemistry Laboratory
Troy Chemistry Laboratory
Wayne Chemistry Laboratory
Performed
Sunday – Saturday, 24 hours a day.
STAT results available within 1 hour of receipt in the Laboratory.
Routine results available within 4 hours.
Reference Range
Therapeutic Range: 0.8-2.0 ng/mL.
Critical Values
Patients 0-70 Years: Greater than 2.5 ng/mL.
Patients Greater than 70 Years: Greater than 2.0 ng/mL.
Test Methodology
Particle Enhanced Turbidimetric Inhibition Immunoassay.
Interpretation
Digoxin clearance is related to renal function. Renal disease or advanced age may necessitate a dose reduction. Blood samples drawn less than six hours post administration may be falsely elevated.
Clinical Utility
This assay is used to monitor the therapeutic drug level and evaluate the toxicity of digoxin. Digoxin is a cardiac glycoside that is commonly prescribed to treat congestive heart failure.
CPT Codes
80162
LOINC: 10535-3
Contacts
Livonia Laboratory – LVA
947-523-4370
Name: Livonia Laboratory – LVA
Location:
Phone: 947-523-4370
STAT Laboratory – RO
248-898-0325
Name: STAT Laboratory – RO
Location:
Phone: 248-898-0325
Lenox Laboratory – LNX
947-523-4070
Name: Lenox Laboratory – LNX
Location:
Phone: 947-523-4070
Chemistry Laboratory – TRN
734-671-3165
Name: Chemistry Laboratory – TRN
Location:
Phone: 734-671-3165
Chemistry Laboratory – DBN
313-436-2196
Name: Chemistry Laboratory – DBN
Location:
Phone: 313-436-2196
Chemistry Laboratory – TYL
313-295-5360
Name: Chemistry Laboratory – TYL
Location:
Phone: 313-295-5360
Main Laboratory –WYN
734-467-4274
Name: Main Laboratory –WYN
Location:
Phone: 734-467-4274
Canton Laboratory – CTN
734-454-8024
Name: Canton Laboratory – CTN
Location:
Phone: 734-454-8024
Chemistry Laboratory – FH
947-521-5252
Name: Chemistry Laboratory – FH
Location:
Phone: 947-521-5252
Chemistry Laboratory – GP
313-473-1807
Name: Chemistry Laboratory – GP
Location:
Phone: 313-473-1807
Chemistry Laboratory – TR
248-964-8070
Name: Chemistry Laboratory – TR
Location:
Phone: 248-964-8070
Last Updated
10/3/2023
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