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Cystine, Urine Quantitative

Test Codes

EPIC: LAB5999, Beaker: XCYSU, ARUP: 81106

Department

Send Outs

Instructions

• Use for monitoring treatment of patients previously diagnosed with cystinuria.
• A Urine Creatinine test is performed on each sample.
• Please refer to the Specimen Collection Manual for instructions on 24 Hour Urine Collection:
  • Urine 24-Hour Collection - Inpatient.
  • Urine 24-Hour Collection - Outpatient.
  • Urine 24-Hour Collection - Outreach.

Specimen Collection Criteria

Collect: 24-hour urine sample with no preservative.

• Keep 24-hour urine specimen iced or refrigerated during collection.
• Include start and end dates and times for the collection period on the specimen container.
• Critical frozen. Specimens must be delivered to the Laboratory immediately after completion of collection.

Urine Preservative Options
No Preservative	6N Hydrochloric Acid	Boric Acid (10g)	Sodium Carbonate	50% Acetic Acid
REQUIRED	Unacceptable	Unacceptable	Unacceptable	Unacceptable

Physician Office/Draw Specimen Preparation

Maintain specimens frozen (-20°C/-4°F or below) prior to transport.

Preparation for Courier Transport

Transport: Entire 24-hour urine collection, frozen (-20°C/-4°F or below).

Rejection Criteria

• Random urine samples.
• Urine with any type of preservative.
• Specimens not collected and processed as indicated.

In-Lab Processing

Measure total volume of 24-hour urine specimen. Record total volume and collection start and end dates and times in the LIS system. Aliquot 8.0 mL from the well-mixed 24-hour urine collection and freeze (-20°C/-4°F or below). (Minimum: 3.0 mL)

Storage

Specimen Stability for Testing:

Room temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): 30 days

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT.

Performed

Monday – Friday.
Results available in 4-8 days.

Reference Range

By report.

Test Methodology

Liquid Chromatography/Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

This test is indicated only to monitor patients with cystinuria on therapy.

CPT Codes

82131
LOINC:  22672-0, 30065-7

Contacts

Last Updated

10/3/2023